acridines

acridines
Heterocyclic compounds with a pyridine nucleus. Usually fluorescent and reactive with double stranded DNA as intercalating agents at very low concentrations. Hence dsDNA can be detected on gels by fluorescence after acridine staining. Mutagenic (causing frame-shift mutations ), cytostatic (and hence antimicrobial). They also affect RNA synthesis and have been used for cell marking.

Dictionary of molecular biology. 2004.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Creosote — For other uses, see Creosote (disambiguation). Creosote is the portion of chemical products obtained by the distillation of a tar that remains heavier than water, notably useful for its anti septic and preservative properties.[1] It is produced… …   Wikipedia

  • DNA — For a non technical introduction to the topic, see Introduction to genetics. For other uses, see DNA (disambiguation). The structure of the DNA double helix. The atoms in the structure are colour coded by element and the detailed structure of two …   Wikipedia

  • Acridine — Chembox new ImageFile=Acridine chemical structure.png ImageSize=250px IUPACName=Acridine OtherNames= Section1= Chembox Identifiers CASNo=260 94 6 PubChem=9215 SMILES=C1=CC=C2C(=C1)C=C3C=CC=CC3=N2 Section2= Chembox Properties C=13|H=9|N=1… …   Wikipedia

  • Quinacrine — Systematic (IUPAC) name (RS) N (6 chloro 2 methoxy acridin 9 yl) N, N diethyl pentane 1,4 diamine Clinical data Trade names …   Wikipedia

  • Intercalation (chemistry) — Intercalation induces structural distortions. Left: unchanged DNA strand. Right: DNA strand intercalated at three locations (red areas). In chemistry, intercalation is the reversible inclusion of a molecule (or group) between two other molecules… …   Wikipedia

  • Arene substitution patterns — are part of organic chemistry IUPAC nomenclature and pinpoint the position of substituents other than hydrogen in relation to each other on an aromatic hydrocarbon. Contents 1 Ortho, meta, and para substitution 2 Ipso, meso, and peri substitution …   Wikipedia

  • Leonard Lerman — is an American scientist most noted for his work on DNA.As a graduate student with Linus Pauling at the California Institute of Technology, Lerman discovered that antibodies have two binding sites. Later, perhaps his most important discovery was… …   Wikipedia

  • 260-94-6 — Acridine Acridine Structure de l acridine Général Nom IUPAC Acridine …   Wikipédia en Français

  • Acridine — Structure de l acridine Général Nom IUPAC Acridine …   Wikipédia en Français

  • C13H9N — Acridine Acridine Structure de l acridine Général Nom IUPAC Acridine …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”